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Galectin-1 triggers an immunoregulatory signature in T helper cells functionally defined by IL-10 expression

Galectin-1 (Gal-1), aβ-galactoside-binding protein, can alter fate and effector function of T helper (Th) cells; however, little is known about how Gal-1 induces Th cell differentiation. Here, we show that both uncommitted and polarized Th cells bound by Gal-1 expressed an immunoregulatory signature...

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書誌詳細
主要な著者: Cedeno-Laurent, Filiberto, Opperman, Matthew, Barthel, Steven R., Kuchroo, Vijay K., Dimitroff, Charles J.
フォーマット: Artigo
言語:Inglês
出版事項: 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3311782/
https://ncbi.nlm.nih.gov/pubmed/22345665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1103433
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