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Galectin-1 triggers an immunoregulatory signature in T helper cells functionally defined by IL-10 expression
Galectin-1 (Gal-1), aβ-galactoside-binding protein, can alter fate and effector function of T helper (Th) cells; however, little is known about how Gal-1 induces Th cell differentiation. Here, we show that both uncommitted and polarized Th cells bound by Gal-1 expressed an immunoregulatory signature...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3311782/ https://ncbi.nlm.nih.gov/pubmed/22345665 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1103433 |
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