Metabolic inhibition of galectin-1-binding carbohydrates accentuates anti-tumor immunity

Galectin-1 (Gal-1) has been shown to play a major role in tumor immune escape by inducing apoptosis of effector leukocytes and correlating with tumor aggressiveness and disease progression. Targeting the Gal-1 – Gal-1 ligand axis, thus, represents a promising cancer therapeutic approach. Here, to te...

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Detalhes bibliográficos
Main Authors: Cedeno-Laurent, Filiberto, Opperman, Matthew, Barthel, Steven R., Hays, Danielle, Schatton, Tobias, Zhan, Qian, He, Xiaoying, Matta, Khushi L., Supko, Jeffrey G., Frank, Markus H., Murphy, George F., Dimitroff, Charles J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3258338/
https://ncbi.nlm.nih.gov/pubmed/22158550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2011.335
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