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IL-12– and IL-23–induced T helper cell subsets: birds of the same feather flock together

Traditionally, CD4(+) T cells have been separated into two different subsets named T helper (Th)1 and Th2. A new IL-23–driven subset of Th cells called Th(IL-17) has now been described. The data suggest that IL-23 plays an important role in the differentiation of autoreactive pathogenic T cells. Whe...

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Autors principals: Bettelli, Estelle, Kuchroo, Vijay K.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2005
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212800/
https://ncbi.nlm.nih.gov/pubmed/15657286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20042279
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