Type I interferon drives a distinctive dendritic cell maturation phenotype that allows continued class II MHC synthesis and antigen processing

Microbial molecules or cytokines can stimulate dendritic cell (DC) maturation, which involves DC migration to lymph nodes and enhanced presentation of Ag to launch T cell responses. Microbial Toll-like receptor (TLR) agonists are the most studied inducers of DC maturation, but type I interferon (IFN...

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Hlavní autoři: Simmons, Daimon P., Wearsch, Pamela A., Canaday, David H., Meyerson, Howard J., Liu, Yi C., Wang, Ying, Boom, W. Henry, Harding, Clifford V.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3311734/
https://ncbi.nlm.nih.gov/pubmed/22371391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1101313
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