Mycobacterium bovis BCG decreases MHC-II expression in vivo on murine lung macrophages and dendritic cells during aerosol infection

Mycobacterium tuberculosis and M. bovis BCG infect APCs. In vitro, mycobacteria inhibit IFN-gamma-induced MHC-II expression by macrophages, but the effects of mycobacteria on lung APCs in vivo remain unclear. To assess MHC-II expression on APCs infected in vivo, mice were aerosol-infected with GFP-e...

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Auteurs principaux: Pecora, Nicole D., Fulton, Scott A., Reba, Scott M., Drage, Michael G., Simmons, Daimon P., Urankar-Nagy, Nancy J., Boom, W. Henry, Harding, Clifford V.
Format: Artigo
Langue:Inglês
Publié: 2008
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2653222/
https://ncbi.nlm.nih.gov/pubmed/18762288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellimm.2008.07.002
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