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2,3,7,8-Tetrachlorodibenzo-p-dioxin Induces Transcriptional Activity of the Human Polymorphic hs1,2 Enhancer of the 3’Igh Regulatory Region

2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) is an environmental toxicant known to inhibit antibody secretion and Ig expression. Inhibition of Ig expression may be partially mediated through repression of the 3’Igh regulatory region (3’IghRR). TCDD inhibits mouse 3’IghRR activation and induces aryl hy...

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Detaylı Bibliyografya
Asıl Yazarlar: Fernando, Tharu, Ochs, Sharon, Liu, Jing, Chambers-Turner, Ruth, Sulentic, Courtney E.W.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3311717/
https://ncbi.nlm.nih.gov/pubmed/22357631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1101111
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