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2,3,7,8-Tetrachlorodibenzo-p-dioxin Induces Transcriptional Activity of the Human Polymorphic hs1,2 Enhancer of the 3’Igh Regulatory Region

2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) is an environmental toxicant known to inhibit antibody secretion and Ig expression. Inhibition of Ig expression may be partially mediated through repression of the 3’Igh regulatory region (3’IghRR). TCDD inhibits mouse 3’IghRR activation and induces aryl hy...

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Bibliografiska uppgifter
Huvudupphovsmän: Fernando, Tharu, Ochs, Sharon, Liu, Jing, Chambers-Turner, Ruth, Sulentic, Courtney E.W.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2012
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3311717/
https://ncbi.nlm.nih.gov/pubmed/22357631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1101111
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