A dioxin response element in the multiple cloning site of the pGL3 luciferase reporter influences transcriptional activity

Luciferase reporter plasmids (pGL3 backbone, Promega) have been utilized to characterize the transcriptional effects of the environmental contaminant 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and other aryl hydrocarbon receptor (AhR) ligands. Following ligand activation, the AhR and its dimerizatio...

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Hlavní autoři: Ochs, Sharon, Liu, Jing, Fernando, Tharu, Fecher, Roger, Sulentic, Courtney E.W.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3398214/
https://ncbi.nlm.nih.gov/pubmed/22652426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tiv.2012.05.007
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