Puerarin Induces Mitochondria-Dependent Apoptosis in Hypoxic Human Pulmonary Arterial Smooth Muscle Cells

BACKGROUND: Pulmonary vascular medial hypertrophy in hypoxic pulmonary arterial hypertension (PAH) is caused in part by decreased apoptosis in pulmonary artery smooth muscle cells (PASMCs). Puerarin, an isoflavone purified from the Chinese medicinal herb kudzu, ameliorates chronic hypoxic PAH in ani...

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Autors principals: Chen, Chan, Chen, Chun, Wang, Zhiyi, Wang, Liangxing, Yang, Lehe, Ding, Minjiao, Ding, Cheng, Sun, Yu, Lin, Quan, Huang, Xiaoying, Du, Xiaohong, Zhao, Xiaowei, Wang, Chuangyi
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3311615/
https://ncbi.nlm.nih.gov/pubmed/22457823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0034181
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