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The Role of Mitochondria in Apoptosis()

Mitochondria play key roles in activating apoptosis in mammalian cells. Bcl-2 family members regulate the release of proteins from the space between the mitochondrial inner and outer membrane that, once in the cytosol, activate caspase proteases that dismantle cells and signal efficient phagocytosis...

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Bibliografiska uppgifter
I publikationen:Annu Rev Genet
Huvudupphovsmän: Wang, Chunxin, Youle, Richard J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2009
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4762029/
https://ncbi.nlm.nih.gov/pubmed/19659442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-genet-102108-134850
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