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The Role of Mitochondria in Apoptosis()

Mitochondria play key roles in activating apoptosis in mammalian cells. Bcl-2 family members regulate the release of proteins from the space between the mitochondrial inner and outer membrane that, once in the cytosol, activate caspase proteases that dismantle cells and signal efficient phagocytosis...

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Detalles Bibliográficos
Publicado en:Annu Rev Genet
Autores principales: Wang, Chunxin, Youle, Richard J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4762029/
https://ncbi.nlm.nih.gov/pubmed/19659442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-genet-102108-134850
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