C/EBPβ suppression by interruption of CUGBP1 resulting from a complex rearrangement of MLL

Translocations involving the mixed-lineage leukemia gene (MLL) confer a poor prognosis in acute leukemias. In t(1;11)(q21;q23), MLL is fused reciprocally with AF1q. Here we describe a t(1;11)(q21;q23) with a secondary event involving insertion of the telomeric portion of MLL into the p arm of chromo...

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Hauptverfasser: Choi, William T., Folsom, Matthew R., Azim, Mohammed F., Meyer, Claus, Kowarz, Eric, Marschalek, Rolf, Timchenko, Nikolai A., Naeem, Rizwan C., Lee, Dean A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3311538/
https://ncbi.nlm.nih.gov/pubmed/17854664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cancergencyto.2007.07.002
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