ARID5B polymorphism confers an increased risk to acquire specific MLL rearrangements in early childhood leukemia

BACKGROUND: Acute leukemia in early age (EAL) is characterized by acquired genetic alterations such as MLL rearrangements (MLL-r). The aim of this case-controlled study was to investigate whether single nucleotide polymorphisms (SNPs) of IKZF1, ARID5B, and CEBPE could be related to the onset of EAL...

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Hauptverfasser: Emerenciano, Mariana, Barbosa, Thayana Conceição, Lopes, Bruno Almeida, Blunck, Caroline Barbieri, Faro, Alessandra, Andrade, Camilla, Meyer, Claus, Marschalek, Rolf, Pombo-de-Oliveira, Maria S
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2014
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3948138/
https://ncbi.nlm.nih.gov/pubmed/24564228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-127
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