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Nucleoprotein complex intermediates in HIV-1 integration
Integration of retroviral DNA into the host genome is an essential step in the viral replication cycle. The viral DNA, made by reverse transcription in the cytoplasm, forms part of a large nucleoprotein complex called the preintegration complex (PIC). The viral integrase protein is the enzyme within...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2009
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3311468/ https://ncbi.nlm.nih.gov/pubmed/19232539 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2009.02.001 |
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