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Defining the molecular interface that connects the Fanconi anemia protein FANCM to the Bloom syndrome dissolvasome
The RMI subcomplex (RMI1/RMI2) functions with the BLM helicase and topoisomerase IIIα in a complex called the “dissolvasome,” which separates double-Holliday junction DNA structures that can arise during DNA repair. This activity suppresses potentially harmful sister chromatid exchange (SCE) events...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3311393/ https://ncbi.nlm.nih.gov/pubmed/22392978 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1117279109 |
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