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Defining the molecular interface that connects the Fanconi anemia protein FANCM to the Bloom syndrome dissolvasome

The RMI subcomplex (RMI1/RMI2) functions with the BLM helicase and topoisomerase IIIα in a complex called the “dissolvasome,” which separates double-Holliday junction DNA structures that can arise during DNA repair. This activity suppresses potentially harmful sister chromatid exchange (SCE) events...

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Detalhes bibliográficos
Main Authors: Hoadley, Kelly A., Xue, Yutong, Ling, Chen, Takata, Minoru, Wang, Weidong, Keck, James L.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3311393/
https://ncbi.nlm.nih.gov/pubmed/22392978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1117279109
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