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Promiscuous binding of extracellular peptides to cell surface class I MHC protein
Algorithms derived from measurements of short-peptide (8–10 mers) binding to class I MHC proteins suggest that the binding groove of a class I MHC protein, such as K(b), can bind well over 1 million different peptides with significant affinity (<500 nM), a level of ligand-binding promiscuity appr...
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| 主要な著者: | , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3311345/ https://ncbi.nlm.nih.gov/pubmed/22403068 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1201586109 |
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