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Stage-dependent reactivity of thymocytes to self-peptide–MHC complexes

In mice that express a transgene for the 2C T cell antigen-receptor (TCR) and lack a recombinase-activating gene (2C(+)RAG(−/−) mice) most of the peripheral T cells are CD8(+), a few are CD4(+), and a significant fraction are CD4(−)CD8(−) [double negative (DN)]. The DN 2C cells, like DN T cells that...

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Sonraí Bibleagrafaíochta
Main Authors: Leng, Qibin, Ge, Qing, Nguyen, Tam, Eisen, Herman N., Chen, Jianzhu
Formáid: Artigo
Teanga:Inglês
Foilsithe: National Academy of Sciences 2007
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1829260/
https://ncbi.nlm.nih.gov/pubmed/17360333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0700674104
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