12/15-Lipoxygenase signaling in the endoplasmic reticulum stress response

Central obesity is associated with chronic inflammation, insulin resistance, β-cell dysfunction, and endoplasmic reticulum (ER) stress. The 12/15-lipoxygenase enzyme (12/15-LO) promotes inflammation and insulin resistance in adipose and peripheral tissues. Given that obesity is associated with ER st...

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Bibliographic Details
Main Authors: Cole, Banumathi K., Kuhn, Norine S., Green-Mitchell, Shamina M., Leone, Kendall A., Raab, Rebekah M., Nadler, Jerry L., Chakrabarti, Swarup K.
Format: Artigo
Language:Inglês
Published: American Physiological Society 2012
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3311293/
https://ncbi.nlm.nih.gov/pubmed/22215650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00373.2011
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