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12/15-Lipoxygenase Products Induce Inflammation and Impair Insulin Signaling in 3T3-L1 Adipocytes

Inflammation and insulin resistance associated with visceral obesity are important risk factors for the development of type 2 diabetes, atherosclerosis, and the metabolic syndrome. The 12/15-lipoxygenase (12/15-LO) enzyme has been linked to inflammatory changes in blood vessels that precede the deve...

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Detalhes bibliográficos
Main Authors: Chakrabarti, Swarup K., Cole, Banumathi K., Wen, Yeshao, Keller, Susanna R., Nadler, Jerry L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2887741/
https://ncbi.nlm.nih.gov/pubmed/19521344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/oby.2009.192
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