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HIF1α is required for survival maintenance of chronic myeloid leukemia stem cells
Hypoxia-inducible factor-1α (HIF1α), a master transcriptional regulator of the cellular and systemic hypoxia response, is essential for the maintenance of self-renewal capacity of normal HSCs. It is still unknown whether HIF1α has a role in survival regulation of leukemia stem cells (LSCs) in chroni...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society of Hematology
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3311277/ https://ncbi.nlm.nih.gov/pubmed/22275380 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-10-387381 |
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