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Rantes/Ccl5 influences hematopoietic stem cell subtypes and causes myeloid skewing
HSCs undergo dramatic changes with aging. An increase in absolute numbers of HSCs along with a functional deficit in reconstitution potential and a shift toward production of myeloid cells are the hallmarks of murine hematopoietic aging. Here, we show that high levels of the inflammatory cytokine Ra...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society of Hematology
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3311273/ https://ncbi.nlm.nih.gov/pubmed/22289892 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-11-391730 |
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