High-resolution genomic profiling of adult and pediatric core-binding factor acute myeloid leukemia reveals new recurrent genomic alterations

To identify cooperating lesions in core-binding factor acute myeloid leukemia, we performed single-nucleotide polymorphism-array analysis on 300 diagnostic and 41 relapse adult and pediatric leukemia samples. We identified a mean of 1.28 copy number alterations per case at diagnosis in both patient...

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Bibliografiske detaljer
Main Authors: Kühn, Michael W. M., Radtke, Ina, Bullinger, Lars, Goorha, Salil, Cheng, Jinjun, Edelmann, Jennifer, Gohlke, Juliane, Su, Xiaoping, Paschka, Peter, Pounds, Stanley, Krauter, Jürgen, Ganser, Arnold, Quessar, Asmaa, Ribeiro, Raul, Gaidzik, Verena I., Shurtleff, Sheila, Krönke, Jan, Holzmann, Karlheinz, Ma, Jing, Schlenk, Richard F., Rubnitz, Jeffrey E., Döhner, Konstanze, Döhner, Hartmut, Downing, James R.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2012
Fag:
Myeloid Neoplasia
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3311263/
https://ncbi.nlm.nih.gov/pubmed/22234698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-09-380444
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