High-resolution genomic profiling of adult and pediatric core-binding factor acute myeloid leukemia reveals new recurrent genomic alterations

To identify cooperating lesions in core-binding factor acute myeloid leukemia, we performed single-nucleotide polymorphism-array analysis on 300 diagnostic and 41 relapse adult and pediatric leukemia samples. We identified a mean of 1.28 copy number alterations per case at diagnosis in both patient...

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Detalhes bibliográficos
Principais autores: Kühn, Michael W. M., Radtke, Ina, Bullinger, Lars, Goorha, Salil, Cheng, Jinjun, Edelmann, Jennifer, Gohlke, Juliane, Su, Xiaoping, Paschka, Peter, Pounds, Stanley, Krauter, Jürgen, Ganser, Arnold, Quessar, Asmaa, Ribeiro, Raul, Gaidzik, Verena I., Shurtleff, Sheila, Krönke, Jan, Holzmann, Karlheinz, Ma, Jing, Schlenk, Richard F., Rubnitz, Jeffrey E., Döhner, Konstanze, Döhner, Hartmut, Downing, James R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2012
Assuntos:
Myeloid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3311263/
https://ncbi.nlm.nih.gov/pubmed/22234698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-09-380444
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