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CD300a and CD300f differentially regulate the MyD88 and TRIF-mediated TLR signalling pathways through activation of SHP-1 and/or SHP-2 in human monocytic cell lines

CD300a, a membrane protein expressed on myeloid lineages and specific subsets of CD4(+) T cells, has been reported to have inhibitory activities in cellular activation. However, the role of CD300a in Toll-like receptor (TLR) -mediated macrophage activation has not been investigated. The human monocy...

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Podrobná bibliografie
Hlavní autoři: Kim, Eun-Ju, Lee, Sang-Min, Suk, Kyoungho, Lee, Won-Ha
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Publishing Ltd 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3311045/
https://ncbi.nlm.nih.gov/pubmed/22043923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2011.03528.x
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