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TLR4, TRIF, and MyD88 are essential for myelopoiesis and CD11c(+) adipose tissue macrophage production in obese mice
Obesity-induced chronic inflammation is associated with metabolic disease. Results from mouse models utilizing a high-fat diet (HFD) have indicated that an increase in activated macrophages, including CD11c(+) adipose tissue macrophages (ATMs), contributes to insulin resistance. Obesity primes myelo...
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| 出版年: | J Biol Chem |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Biochemistry and Molecular Biology
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5995515/ https://ncbi.nlm.nih.gov/pubmed/29636416 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.001526 |
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