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TLR9/MyD88/TRIF signaling activates host immune inhibitory CD200 in Leishmania infection
Virulent protozoans named Leishmania in tropical and subtropical areas produce devastating diseases by exploiting host immune responses. Amastigotes of Leishmania amazonensis stimulate macrophages to express CD200, an immunomodulatory ligand, which binds to its cognate receptor (CD200R) and inhibits...
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| Pubblicato in: | JCI Insight |
|---|---|
| Autori principali: | , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Clinical Investigation
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6542632/ https://ncbi.nlm.nih.gov/pubmed/31092731 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.126207 |
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