TLR9/MyD88/TRIF signaling activates host immune inhibitory CD200 in Leishmania infection

Virulent protozoans named Leishmania in tropical and subtropical areas produce devastating diseases by exploiting host immune responses. Amastigotes of Leishmania amazonensis stimulate macrophages to express CD200, an immunomodulatory ligand, which binds to its cognate receptor (CD200R) and inhibits...

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Detaylı Bibliyografya
Yayımlandı:JCI Insight
Asıl Yazarlar: Sauter, Ismael P., Madrid, Katerine G., de Assis, Josiane B., Sá-Nunes, Anderson, Torrecilhas, Ana C., Staquicini, Daniela I., Pasqualini, Renata, Arap, Wadih, Cortez, Mauro
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 2019
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6542632/
https://ncbi.nlm.nih.gov/pubmed/31092731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.126207
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