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An improved procedure for derivatization of controlled-pore glass beads for solid-phase oligonucleotide synthesis.

A simplified and economical method for the attachment of 2'-deoxyribo, ribo and arabinonucleosides onto long-chain alkylamidopropanoic acid controlled-pore glass (LCAAP-CPG, P-3) is described. In this procedure, 5'-O-tritylated nucleosides are coupled directly to LCAAP-CPG in excellent yie...

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Hlavní autoři: Damha, M J, Giannaris, P A, Zabarylo, S V
Médium: Artigo
Jazyk:Inglês
Vydáno: 1990
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC331081/
https://ncbi.nlm.nih.gov/pubmed/2374710
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