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Synthesis, hybridization properties and antiviral activity of lipid-oligodeoxynucleotide conjugates.
Triethylammonium 1,2-di-O-hexadecyl-rac-glycero-3-H-phosphonate (2) was coupled to the 5' terminus of oligodeoxynucleotides via hydrogen phosphonate solid support DNA synthesis methodology. Duplex DNA oligomers with a single 5'-phospholipid melted at lower temperatures than the correspondi...
Kaydedildi:
| Asıl Yazarlar: | , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
1990
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| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC331077/ https://ncbi.nlm.nih.gov/pubmed/2165251 |
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