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Discriminatory accuracy and potential clinical utility of genomic profiling for breast cancer risk in BRCA-negative women

Several single nucleotide polymorphisms (SNPs) are associated with an increased risk of breast cancer. The clinical utility of genotyping individuals at these loci is not known. Subjects were 519 unaffected women without BRCA mutations. Gail, Claus, and IBIS models were used to estimate absolute bre...

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書誌詳細
主要な著者: Comen, E., Balistreri, L., Gönen, M., Dutra-Clarke, A., Fazio, M., Vijai, J., Stadler, Z., Kauff, N., Kirchhoff, T., Hudis, C., Offit, K., Robson, M.
フォーマット: Artigo
言語:Inglês
出版事項: 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3310430/
https://ncbi.nlm.nih.gov/pubmed/20957429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-010-1215-2
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