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Discriminatory accuracy and potential clinical utility of genomic profiling for breast cancer risk in BRCA-negative women
Several single nucleotide polymorphisms (SNPs) are associated with an increased risk of breast cancer. The clinical utility of genotyping individuals at these loci is not known. Subjects were 519 unaffected women without BRCA mutations. Gail, Claus, and IBIS models were used to estimate absolute bre...
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| Asıl Yazarlar: | , , , , , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2010
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3310430/ https://ncbi.nlm.nih.gov/pubmed/20957429 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-010-1215-2 |
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