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Post-Aire Maturation of Thymic Medullary Epithelial Cells Involves Selective Expression of Keratinocyte-Specific Autoantigens

The autoimmune regulator (Aire)-directed ectopic expression of tissue-specific antigens (TSAs) by mature medullary thymic epithelial cells (mTECs) has been viewed as an essential mechanism in the induction of central tolerance. Recent data suggest that the survival of mTECs extends beyond the Aire+...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Wang, Xiaoping, Laan, Martti, Bichele, Rudolf, Kisand, Kai, Scott, Hamish S., Peterson, Pärt
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Frontiers Research Foundation 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3310317/
https://ncbi.nlm.nih.gov/pubmed/22448160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2012.00019
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