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Aire deficiency results in decreased expression of CCR4 and CCR7 ligands and in delayed migration of CD4+ thymocytes
Autoimmune regulator (Aire) has been viewed as a central player in the induction of tolerance. This study examines, whether Aire can modulate the production of the thymic chemokines involved in cortico-medullary migration and thus play a role in intrathymic thymocyte migration and maturation. Aire d...
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| Main Authors: | , , , , , , |
|---|---|
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2795747/ https://ncbi.nlm.nih.gov/pubmed/19923453 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0804133 |
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