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Post-Aire Medullary Thymic Epithelial Cells and Hassall’s Corpuscles as Inducers of Tonic Pro-Inflammatory Microenvironment

While there is convincing evidence on the role of Aire-positive medullary thymic epithelial cells (mTEC) in the induction of central tolerance, the nature and function of post-Aire mTECs and Hassall’s corpuscles have remained enigmatic. Here we summarize the existing data on these late stages of mTE...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Laan, Martti, Salumets, Ahto, Klein, Annabel, Reintamm, Kerli, Bichele, Rudolf, Peterson, Hedi, Peterson, Pärt
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8050345/
https://ncbi.nlm.nih.gov/pubmed/33868260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.635569
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