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Elucidation of common pharmacophores from analysis of targeted metabolites transported by the multispecific drug transporter—Organic anion transporter1 (Oat1)

Organic anion transporter 1 (Oat1), first identified as NKT, is a multispecific transporter responsible for the handling of drugs and toxins in the kidney and choroid plexus, but its normal physiological role appears to be in small molecule metabolite regulation. Metabolites transported by Oat1 and...

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Main Authors: Kouznetsova, Valentina L., Tsigelny, Igor F., Nagle, Megha A., Nigam, Sanjay K.
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3310230/
https://ncbi.nlm.nih.gov/pubmed/21571536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2011.04.045
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