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Modulation of Apoptosis Pathways by Oxidative Stress and Autophagy in β Cells
Human islets isolated for transplantation are exposed to multiple stresses including oxidative stress and hypoxia resulting in significant loss of functional β cell mass. In this study we examined the modulation of apoptosis pathway genes in islets exposed to hydrogen peroxide, peroxynitrite, hypoxi...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Hindawi Publishing Corporation
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3310197/ https://ncbi.nlm.nih.gov/pubmed/22474427 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/647914 |
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