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Modulation of Apoptosis Pathways by Oxidative Stress and Autophagy in β Cells

Human islets isolated for transplantation are exposed to multiple stresses including oxidative stress and hypoxia resulting in significant loss of functional β cell mass. In this study we examined the modulation of apoptosis pathway genes in islets exposed to hydrogen peroxide, peroxynitrite, hypoxi...

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Détails bibliographiques
Auteurs principaux: Wang, Maorong, Crager, Mia, Pugazhenthi, Subbiah
Format: Artigo
Langue:Inglês
Publié: Hindawi Publishing Corporation 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3310197/
https://ncbi.nlm.nih.gov/pubmed/22474427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/647914
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