Amyloid Beta and Tau Proteins as Therapeutic Targets for Alzheimer's Disease Treatment: Rethinking the Current Strategy

Alzheimer's disease (AD) is defined by the concurrence of accumulation of abnormal aggregates composed of two proteins: Amyloid beta (Aβ) and tau, and of cellular changes including neurite degeneration and loss of neurons and cognitive functions. Based on their strong association with disease,...

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Hlavní autoři: Mondragón-Rodríguez, Siddhartha, Perry, George, Zhu, Xiongwei, Boehm, Jannic
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2012
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Review Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3310047/
https://ncbi.nlm.nih.gov/pubmed/22482074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/630182
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