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Amyloid Beta and Tau Proteins as Therapeutic Targets for Alzheimer's Disease Treatment: Rethinking the Current Strategy

Alzheimer's disease (AD) is defined by the concurrence of accumulation of abnormal aggregates composed of two proteins: Amyloid beta (Aβ) and tau, and of cellular changes including neurite degeneration and loss of neurons and cognitive functions. Based on their strong association with disease,...

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Detalhes bibliográficos
Main Authors: Mondragón-Rodríguez, Siddhartha, Perry, George, Zhu, Xiongwei, Boehm, Jannic
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3310047/
https://ncbi.nlm.nih.gov/pubmed/22482074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/630182
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