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Induction of Protective CD4(+) T Cell-Mediated Immunity by a Leishmania Peptide Delivered in Recombinant Influenza Viruses
The available evidence suggests that protective immunity to Leishmania is achieved by priming the CD4(+) Th1 response. Therefore, we utilised a reverse genetics strategy to generate influenza A viruses to deliver an immunogenic Leishmania peptide. The single, immunodominant Leishmania-specific LACK(...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3310046/ https://ncbi.nlm.nih.gov/pubmed/22470440 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0033161 |
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