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Systematic identification of immunodominant CD8(+) T-cell responses to influenza A virus in HLA-A2 individuals

Immunodominant T-cell responses are important for virus clearance. However, the identification of immunodominant T-cell peptide + HLA glycoprotein epitopes has been hindered by the extent of HLA polymorphism and the limitations of predictive algorithms. A simple, systematic approach has been used he...

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Hlavní autoři: Wu, Chao, Zanker, Damien, Valkenburg, Sophie, Tan, Bee, Kedzierska, Katherine, Zou, Quan Ming, Doherty, Peter C., Chen, Weisan
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3107317/
https://ncbi.nlm.nih.gov/pubmed/21562214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1105624108
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