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Overlapping functions between XLF repair protein and 53BP1 DNA damage response factor in end joining and lymphocyte development
Nonhomologous end joining (NHEJ), a major pathway of DNA double-strand break (DSB) repair, is required during lymphocyte development to resolve the programmed DSBs generated during Variable, Diverse, and Joining [V(D)J] recombination. XRCC4-like factor (XLF) (also called Cernunnos or NHEJ1) is a uni...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3309750/ https://ncbi.nlm.nih.gov/pubmed/22355127 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1120160109 |
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