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Proteolytic Regulation of the Mitochondrial cAMP-Dependent Protein Kinase
The mitochondrial cAMP-dependent protein kinase (PKA) is activatable in a cAMP-independent fashion. The regulatory (R) subunits of the PKA holoenzyme (R(2)C(2)), but not the catalytic (C) subunits, suffer proteolysis upon exposure of bovine heart mitochondria to digitonin, Ca(2+), and a myriad of el...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3309167/ https://ncbi.nlm.nih.gov/pubmed/22385295 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi201573k |
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