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Suborganelle Sensing of Mitochondrial cAMP-Dependent Protein Kinase Activity

A fluorescent sensor of protein kinase activity has been developed and used to characterize the compartmentalized location of cAMP-dependent protein kinase activity in mitochondria. The sensor functions via a phosphorylation-induced release of a quencher from a peptide-based substrate, producing a 1...

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Detalhes bibliográficos
Main Authors: Agnes, Richard S., Jernigan, Finith, Shell, Jennifer R., Sharma, Vyas, Lawrence, David S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2862470/
https://ncbi.nlm.nih.gov/pubmed/20380406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja909652q
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