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Suborganelle Sensing of Mitochondrial cAMP-Dependent Protein Kinase Activity
A fluorescent sensor of protein kinase activity has been developed and used to characterize the compartmentalized location of cAMP-dependent protein kinase activity in mitochondria. The sensor functions via a phosphorylation-induced release of a quencher from a peptide-based substrate, producing a 1...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2862470/ https://ncbi.nlm.nih.gov/pubmed/20380406 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja909652q |
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