Epigenetic control of CCR5 transcript levels in immune cells and modulation by small molecules inhibitors

Previously, we have shown that CCR5 transcription is regulated by CREB-1. However, the ubiquitous pattern of CREB-1 expression suggests the involvement of an additional level of transcriptional control in the cell type–specific expression of CCR5. In this study, we show that epigenetic changes (i.e....

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Main Authors: Wierda, Rutger J, Kuipers, Hedwich F, van Eggermond, Marja C J A, Benard, Anne, van Leeuwen, Jan C, Carluccio, Silvia, Geutskens, Sacha B, Jukema, J Wouter, Marquez, Victor E, Quax, Paul H A, van den Elsen, Peter J
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Publishing Ltd 2012
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Original Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3309068/
https://ncbi.nlm.nih.gov/pubmed/22050776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2011.01482.x
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