The Adaptor Molecule Nck Localizes the WAVE Complex to Promote Actin Polymerization during CEACAM3-Mediated Phagocytosis of Bacteria

BACKGROUND: CEACAM3 is a granulocyte receptor mediating the opsonin-independent recognition and phagocytosis of human-restricted CEACAM-binding bacteria. CEACAM3 function depends on an intracellular immunoreceptor tyrosine-based activation motif (ITAM)-like sequence that is tyrosine phosphorylated b...

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Autors principals: Pils, Stefan, Kopp, Kathrin, Peterson, Lisa, Delgado Tascón, Julia, Nyffenegger-Jann, Naja J., Hauck, Christof R.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3308951/
https://ncbi.nlm.nih.gov/pubmed/22448228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0032808
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