Phosphatidylinositol 3′-Kinase Activity Is Critical for Initiating the Oxidative Burst and Bacterial Destruction during CEACAM3-mediated Phagocytosis

Carcinoembryonic antigen-related cell adhesion molecule 3 (CEACAM3) is an immunoglobulin-related receptor expressed on human granulocytes. CEACAM3 functions as a single chain phagocytotic receptor recognizing Gram-negative bacteria such as Neisseria gonorrhoeae, which possess CEACAM-binding adhesins...

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Autors principals: Buntru, Alexander, Kopp, Kathrin, Voges, Maike, Frank, Ronald, Bachmann, Verena, Hauck, Christof R.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2011
Matèries:
Cell Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3059060/
https://ncbi.nlm.nih.gov/pubmed/21216968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.216085
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