Grb14 Is a Negative Regulator of CEACAM3-mediated Phagocytosis of Pathogenic Bacteria

Carcinoembryonic antigen-related cell adhesion molecule 3 (CEACAM3) is a phagocytic receptor on human granulocytes, which mediates the opsonin-independent recognition and internalization of a restricted set of Gram-negative bacteria such as Neisseria gonorrhoeae. In an unbiased screen using a SH2 do...

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Bibliographic Details
Main Authors: Kopp, Kathrin, Buntru, Alexander, Pils, Stefan, Zimmermann, Timo, Frank, Ronald, Zumbusch, Andreas, Hauck, Christof R.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2012
Subjects:
Cell Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3493956/
https://ncbi.nlm.nih.gov/pubmed/22948154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.395228
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