Recombinant Vesicular Stomatitis Virus Vaccine Vectors Expressing Filovirus Glycoproteins Lack Neurovirulence in Nonhuman Primates

The filoviruses, Marburg virus and Ebola virus, cause severe hemorrhagic fever with high mortality in humans and nonhuman primates. Among the most promising filovirus vaccines under development is a system based on recombinant vesicular stomatitis virus (rVSV) that expresses an individual filovirus...

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Bibliografiske detaljer
Main Authors: Mire, Chad E., Miller, Andrew D., Carville, Angela, Westmoreland, Susan V., Geisbert, Joan B., Mansfield, Keith G., Feldmann, Heinz, Hensley, Lisa E., Geisbert, Thomas W.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3308941/
https://ncbi.nlm.nih.gov/pubmed/22448291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0001567
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