Recombinant Vesicular Stomatitis Virus Vaccine Vectors Expressing Filovirus Glycoproteins Lack Neurovirulence in Nonhuman Primates

The filoviruses, Marburg virus and Ebola virus, cause severe hemorrhagic fever with high mortality in humans and nonhuman primates. Among the most promising filovirus vaccines under development is a system based on recombinant vesicular stomatitis virus (rVSV) that expresses an individual filovirus...

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Главные авторы: Mire, Chad E., Miller, Andrew D., Carville, Angela, Westmoreland, Susan V., Geisbert, Joan B., Mansfield, Keith G., Feldmann, Heinz, Hensley, Lisa E., Geisbert, Thomas W.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2012
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3308941/
https://ncbi.nlm.nih.gov/pubmed/22448291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0001567
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