Recombinant Vesicular Stomatitis Virus Vaccine Vectors Expressing Filovirus Glycoproteins Lack Neurovirulence in Nonhuman Primates

The filoviruses, Marburg virus and Ebola virus, cause severe hemorrhagic fever with high mortality in humans and nonhuman primates. Among the most promising filovirus vaccines under development is a system based on recombinant vesicular stomatitis virus (rVSV) that expresses an individual filovirus...

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Detalhes bibliográficos
Main Authors: Mire, Chad E., Miller, Andrew D., Carville, Angela, Westmoreland, Susan V., Geisbert, Joan B., Mansfield, Keith G., Feldmann, Heinz, Hensley, Lisa E., Geisbert, Thomas W.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3308941/
https://ncbi.nlm.nih.gov/pubmed/22448291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0001567
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