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The Mycobacterium tuberculosis Stress Response Factor SigH Is Required for Bacterial Burden as Well as Immunopathology in Primate Lungs
(See the editorial commentary by Kernodle, on pages 1186–8.) Background. Sigma H (sigH) is a major Mycobacterium tuberculosis (Mtb) stress response factor. It is induced in response to heat, oxidative stress, cell wall damage, and hypoxia. Infection of macrophages with the Δ-sigH mutant generates mo...
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Κύριοι συγγραφείς: | , , , , , , , , , , , , , , |
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Μορφή: | Artigo |
Γλώσσα: | Inglês |
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Oxford University Press
2012
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Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3308902/ https://ncbi.nlm.nih.gov/pubmed/22402035 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jis102 |
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