Granuloma Correlates of Protection Against Tuberculosis and Mechanisms of Immune Modulation by Mycobacterium tuberculosis

Background. The BCG vaccine is ineffective against adult tuberculosis. Hence, new antituberculosis vaccines are needed. Correlates of protection against tuberculosis are not known. We studied the effects of BCG vaccination on gene expression in tuberculosis granulomas using macaques. Methods. Macaqu...

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Detalhes bibliográficos
Main Authors: Mehra, Smriti, Alvarez, Xavier, Didier, Peter J., Doyle, Lara A., Blanchard, James L., Lackner, Andrew A., Kaushal, Deepak
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Major Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3633457/
https://ncbi.nlm.nih.gov/pubmed/23255564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jis778
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